Objective:To assess whether patients with liver cirrhosis, a condition which can affect many areas of the body, are being treated with orlistat. The aim was to determine the efficacy and safety of the combination of andlistat, administered with orlistat, versus placebo, in patients with liver cirrhosis.
Study design and participants:Patients were recruited from medical practices in the United Kingdom who were either undergoing orlistat treatment for liver cirrhosis, and who were being treated with a prescription for orlistat. The study was a randomized, double-blind, placebo-controlled, multicentre study with the following inclusion and exclusion criteria: age <18 years; male gender; current and past alcohol consumption within the last 6 months; smoking and alcohol abuse within the last 6 months; and severe liver disease. Patients were treated with orlistat (400 mg, 120 mg, or 120 mg) or placebo (300 mg, 120 mg, or 120 mg) for up to 12 weeks. In the combined treatment group, patients taking both treatments were monitored for adverse events and completed a liver function test, which included blood tests for triglyceride, liver enzymes, and cholesterol, and liver function tests, including liver function tests, liver ultrasonography, and a physical examination.
Results:From July 2010 to December 2012, patients received either orlistat (400 mg, 120 mg, or 120 mg) and were evaluated for efficacy, safety, and adverse events. In the combined treatment group, the mean (95% CI) mean (SD) dose of orlistat was 240 (60) mg, 170 (39) mg, and 170 (39) mg, respectively. The mean (95% CI) mean (SD) mean dose of placebo was 280 (44) mg, 110 (22) mg, and 110 (22) mg, respectively. Patients in the orlistat group were also on average 5.5 (1.3) mg/kg for patients in the placebo group and 2.8 (0.6) mg/kg for patients in the placebo group. In the combined treatment group, the mean (95% CI) mean (SD) dose of orlistat was 3.5 (1.0) mg/kg for patients in the placebo group and 2.2 (0.5) mg/kg for patients in the placebo group. Patients in the placebo group also had a significantly higher mean (95% CI) mean (SD) mean dose of orlistat compared with patients in the placebo group, and a significantly lower mean (95% CI) mean (SD) mean dose of orlistat compared with patients in the placebo group.
Conclusions:Patients in the combined treatment group were more likely to tolerate orlistat than patients in the placebo group, and were generally more likely to have improved liver function tests and/or signs of liver inflammation. The combination of orlistat and placebo was well tolerated and the combination of orlistat and placebo was well tolerated, and both were safe for patients with liver cirrhosis.
Table 1 Clinical data of patients with liver cirrhosis treated with orlistat (40 mg, 120 mg, or 120 mg) and placebo (40 mg, 120 mg, or 120 mg) in a multicentre study.Orlistat has been shown to cause mild side effects in some individuals. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious effects, seek medical attention immediately.
Common side effects of orlistat use include:
More serious side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a serious adverse reaction–or allergic reaction–to this medication and require treatment right away.
Orlistat has been shown to affect the absorption of fat-soluble vitamins (vitamin A, D, E and K). This can prevent individuals taking this medication from receiving valuable nutrients from their food. Your doctor may recommend that you take a multivitamin and beta-carotene supplement along with this medication to ensure that you are receiving adequate nutrition from the food you eat.
As with all medication, inform your health care provider of any medical conditions you are currently managing. Let them know if you have or ever had kidney stones, diabetes, liver disease, gallbladder disease, thyroid disease, or an eating disorder (anorexia or bulimia). In addition, you should tell them if you have ever had an organ transplant, cholestasis (reduced or stopped bile flow), or malabsorption syndrome.
Tell your provider about any and all medication, prescription drugs, and supplements you are taking before starting treatment with orlistat. Orlistat can interact with substances in the body, causing potentially serious adverse reactions. Specifically, you should inform them of any immunosuppressant medication you are currently taking, such as cyclosporine. You should also let your provider know if you are currently taking blood thinners–like warfarin–or diabetes medication–like metformin.
In addition, let your doctor know if you are planning to become pregnant, are pregnant, or are currently breastfeeding before starting treatment with this medication.
paralysisThe gel is for people with mild to severe esophagitis and mild to moderate gastric ulcers. It can also be used for patients with moderate to severe ulcers in the presence of severe gastric ulceration, due to which the patient can be managed by gastric decongestant. For this, a gastric decongestant is usually used.
For people with moderate to severe gastric ulcers, a drug called lansoprazole is usually used. This drug reduces gastric acidity by blocking the enzyme that produces stomach acid. On the other hand, it causes less acid production than the drug itself. This reduces the severity of the infection and provides the patient with less discomfort.
The gel is squeezed out onto a spoon and should be stored at room temperature.
How it works:
The active ingredient in the drug is orlistat, which works by preventing the absorption of food into the gut. This helps to lower the amount of acid produced by the stomach.
It does not cure the infection but reduces it.
When the patient stops taking the drug the symptoms of the infection disappear.
The symptoms of an esophageal ulcer can be seen within a few days of treatment with the drug. However, symptoms can also occur if the drug is stopped suddenly or if the patient has gastrointestinal ulceration or gastritis.
It is important that
the gel is applied directly to the ulcer areabefore eating. This will stop the drug from acting on the ulcer area.
Do not use the gel if you have a stomach ulcer.
For gastric ulcers in the presence of serious gastric ulceration, surgery is usually required. The gel is taken orally with water or a tablet. The drug is injected into the esophagus and then swallowed. The patient should be carefully monitored by the doctor until the ulcer is completely healed.
The gel is usually applied on the upper back with a finger and is usually used once or twice daily. The drug should be taken with food. If a meal is missed, take it with the drug.
Other uses:
The use of a medicine containing orlistat is not recommended in people who have had a stroke or heart attack or who are at risk of having a heart attack or stroke. Other people with a history of gastrointestinal disorders or bleeding disorders, such as peptic ulcer, have also reported feeling bloated and watery.
Please see full patient information for further information.
See also:Pregnancy | Lactation | Breast feeding | Bleeding disorders
The gel is available in the form of a gel, usually a liquid. The gel should be squeezed out onto a spoon, taken with water or other liquids, and should be stored at room temperature. It should be used as soon as possible within a few days to four weeks after treatment is started. The patient should be monitored closely by the doctor until the ulcer is completely healed.
For pregnant women, the use of orlistat may be limited by the risks to the mother and child. It should only be used in the first trimester of pregnancy and only if clearly needed. The drug should be used only when clearly needed. Do not exceed the recommended dose.
The gel should be swallowed as a whole, or as a mixture of two or three drops. The mixture should be taken with water or other liquids.
This medicine is only intended for use in a special patient group. It should only be used in a patient who has not yet had a stroke, heart attack, or gastric ulcer. If you are unsure whether your child needs a medicine containing orlistat for the treatment of their condition, speak to your doctor.
Pregnancy | Breast feeding | Bleeding disorders
The gel should be squeezed out onto a spoon, taken with water or other liquids. The mixture should be swallowed as a whole, or as a mixture of two or three drops.
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Alli is a top weight-loss brand in Turkey,...View MoreAlli is a top weight-loss brand in Turkey, offering a range of effective products. With trusted reviews and a commitment to quality, Alli helps individuals achieve their weight-loss goals safely and efficiently.View LessRead More
Alli is a brand of medication that is used for weight loss. It contains the active ingredient Orlistat, which blocks the absorption of fat in the body. Alli is sold over-the-counter and is meant to be used in combination with a low-fat, reduced-calorie diet and exercise program.
- Alli was launched in 2007 by GlaxoSmithKline.
- It was the first FDA-approved over-the-counter weight loss medication.
- In 2014, ownership of the brand was transferred to the British company Reckitt Benckiser.
- Alli is currently available in the United States, the United Kingdom, and Australia.
Xenical is a prescription weight loss medication that also contains Orlistat as its active ingredient. It is marketed by Roche Pharmaceuticals and is available in many countries around the world.
PhenQ is a weight loss supplement that contains a blend of natural ingredients. It is marketed by a company called Wolfson Berg Limited and is available for purchase online.
Hydroxycut is a brand of weight loss supplements that are marketed by Iovate Health Sciences International. The brand offers a variety of products that contain different active ingredients, such as caffeine and green coffee extract.
Alli Capsules are the brand's flagship product. Each capsule contains 60mg of Orlistat and is meant to be taken with meals that contain fat.
Alli is used for weight loss. It works by blocking the absorption of fat in the body.
Alli is meant to be taken with meals that contain fat. You should also follow a low-fat, reduced-calorie diet and exercise program while taking this medication.
Alli is generally considered safe when used as directed. However, it can cause some side effects, such as diarrhea and abdominal pain.
Studies have shown that people who take Alli in combination with a diet and exercise program can lose up to 5% of their body weight within six months.
No, Alli is not recommended for use during pregnancy or breastfeeding.
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Share ShareRedist motion to reduce the use of antimalarin in women aged 18 and over.
2013-12-25 11:10
Suppose you live in the United States and — you’re thinking about trying antimalarin cream or another cream},{"
If you’re thinking about trying antimalarin cream or a other antimalarial cream, visit your local pharmacy and fill out a questionnaire about your health conditions, prescription.
Stade de France Pharmacy